WWOX anticorps (C-Term)

N° du produit ABIN2788787

Cet anticorps Lapin Polyclonal détecte spécifiquement WWOX dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Porc et Lapin.

Aperçu rapide pour WWOX anticorps (C-Term) (ABIN2788787)

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWOX est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-WWOX anticorps

Épitope: C-Term

Séquence: DDNPTKPTTR QRYDGSTTAM EILQGRDFTG KVVVVTGANS GIGFETAKSF

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against WWOX. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 189 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur WWOX

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Autre désignation: WWOX

Sujet: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90 % identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.
Alias Symbols: D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SDR41C1, WOX1
Protein Interaction Partner: ITCH, TRIM28, HUWE1, UBC, ATM, RPRD2, CYFIP1, SPG20, SNRNP200, ACIN1, SLC4A1AP, DHX30, SCAF8, XRN2, GABARAPL2, SEC23IP, HNRNPUL1, DIDO1, CPSF6, SF3B2, SF3A3, SRSF10, USP39, IGF2BP2, IGF2BP3, IGF2BP1, PAICS, PRPF8, CCT2, CCT7, NOP56, DDX17, SEC23A, BAIAP2,
Protein Size: 189

Poids moléculaire: 21 kDa

ID gène: 51741

NCBI Accession: NM_130791, NP_570607